Concentration expression most commonly used for suspensions?

Concentration expression most commonly used for suspensions?

• A. %w/v
• B. %v/v
• C. %w/w
• D. ppm

Answer: (A)

When a solid is dispersed in a liquid, the amount of active substance is most practically described as a quantity per a given volume of the suspension. The % w/v expression does exactly that: grams of solute per 100 mL of suspension. This makes it straightforward to prepare and label a suspension by stating how many grams of drug are present in a specific volume of the product. Other formats aren’t as fitting here. % w/w would describe mass per total mass, which doesn’t directly convey how much drug is in a given volume of suspension, and the volume aspect becomes less intuitive. % v/v implies a liquid solute in a liquid solvent, which isn’t appropriate when the dispersed phase is solid. ppm is a measure reserved for very dilute mixtures and isn’t the standard for typical pharmaceutical suspensions.

When a solid is dispersed in a liquid, the amount of active substance is most practically described as a quantity per a given volume of the suspension. The % w/v expression does exactly that: grams of solute per 100 mL of suspension. This makes it straightforward to prepare and label a suspension by stating how many grams of drug are present in a specific volume of the product.

Other formats aren’t as fitting here. % w/w would describe mass per total mass, which doesn’t directly convey how much drug is in a given volume of suspension, and the volume aspect becomes less intuitive. % v/v implies a liquid solute in a liquid solvent, which isn’t appropriate when the dispersed phase is solid. ppm is a measure reserved for very dilute mixtures and isn’t the standard for typical pharmaceutical suspensions.